Purine nucleotides
Medchemexpress LLC L-Guanosine | 26578-09-6 | 98.0% | 283.24 | 100 MG
L-Guanosine is the L-configuration of Guanosine, a purine nucleoside. It demonstrates anti-herpesvirus activity and can be used in the preparation of supramolecular hydrogel. This product is a solid, ranging from white to off-white in color, and is intended for research use only.
- Purine nucleoside
- Exhibits anti-herpesvirus activity
- Can be used to prepare supramolecular hydrogel
- Solid appearance, white to off-white color
- Store solid at 4°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC Adenosine amine congener (ADAC) | 96760-69-9 | 99.2% | 1 ML
Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist known for its ability to ameliorate noise- and cisplatin-induced cochlear injury. It also exhibits neuroprotective effects by reducing oxidative stress and inhibiting apoptosis in cochlear tissues, thereby protecting sensory hair cells and strial marginal cells.
- Selective A1 adenosine receptor agonist
- Ameliorates noise-induced cochlear injury
- Reduces cisplatin-induced cochlear injury
- Provides neuroprotective effects
- Reduces oxidative stress in noise-exposed cochlea
- Inhibits glutamate release via presynaptic A1 receptors
- Inhibits voltage-gated Ca2+ channels
- Prevents activation of apoptotic and necrotic cell death pathways
- Mitigates noise-induced hearing loss in a dose- and time-dependent manner
Medchemexpress LLC 7-Methyl-guanosine-5'-triphosphate sodium | 5 MG
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. Its phosphorothioate analog is a potent cap-dependent translation inhibitor.
- Potent cap-dependent translation inhibitor.
Apexbio Technology LLC GTP Solution (100 mM) 250uL
GTP also known as Guanosine-5 -triphosphate can be utilized in various molecular biology applications such as in vitro transcription RNA amplification and siRNA synthesis Additionally GTP plays a critical regulatory role in signal transduction as a phosphate or pyrophosphate messenger it activates G-proteins which subsequently initiate protein kinase-mediated signaling cascades thus influencing cellular behaviors including cell proliferation and differentiation GTP also serves as a high-energy nucleotide precursor participating in enzymatic synthesis processes of DNA and RNA This product is prepared from GTP trisodium salt with purity 99% (HPLC) as a clear colorless aqueous solution at a concentration of 100 mM and pH (25 C) of 7 0 0 1 free from DNase and RNase contamination
Medchemexpress LLC Adenosine receptor inhibitor 2 | 2550401-76-6 | 99.1% | 406.28 | 5 MG
Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor. It exhibits dual affinity toward A1/A2A ARs, with a higher affinity for the A1- than the A2AAR. The compound has Ki values of 52.2 nM for the A1AR and 167 nM for the A2AAR.
- Potent AR inhibitor
- Dual affinity toward A1/A2A ARs
- Higher affinity for A1AR (52.2 nM Ki)
- Lower affinity for A2AAR (167 nM Ki)
- Formula: C17H20BrN5O2
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC ATP dipotassium | 42373-41-1 | 98.7% | 100 MG
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital molecule for energy storage and metabolism in living organisms. It supplies the metabolic energy required to power metabolic pumps and acts as a coenzyme within cells. This compound also plays a crucial role as an endogenous signaling molecule in immunity and inflammation, making it valuable for a wide range of research applications.
- Supports energy storage and metabolism.
- Drives metabolic pumps and acts as a coenzyme.
- Functions as an endogenous signaling molecule in immunity and inflammation.
- Synergistic effect on NLRP3 inflammasome activation with LPS.
- Induces secretion of IL-1β, KC, and MIP-2 from BMDMs.
- Promotes neutrophil chemotaxis.
- Offers protection against bacterial infection in vivo.
- Induces IL-1β, KC, MIP-2 secretion and neutrophil recruitment in vivo.